• Clinical nuclear medicine · Apr 2015

    Case Reports

    Detection of brain metastasis with 68Ga-labeled PSMA ligand PET/CT: a novel radiotracer for imaging of prostate carcinoma.

    • Partha Sarathi Chakraborty, Rajiv Kumar, Madhavi Tripathi, Chandan Jyoti Das, and Chandrasekhar Bal.
    • From the *Departments of Nuclear Medicine and PET and †Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
    • Clin Nucl Med. 2015 Apr 1; 40 (4): 328-9.

    AbstractBrain metastasis in prostate cancer is rare and not expected at initial presentation especially when the patient is asymptomatic for the same. A 45-year-old male patient undergoing initial evaluation for newly diagnosed prostatic adenocarcinoma was referred to our department for 99mTc-MDP bone scintigraphy. As part of the study protocol, he also underwent Glu-NH-CO-NH-Lys-(Ahx)-[Ga-68(HBED-CC)] (68Ga-PSMA) PET/CT, which revealed tracer accumulation in brain lesions, apart from localization in the primary, lymph node, and bone metastases. A subsequent MR evaluation confirmed brain metastases.

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