• European radiology · Jan 2006

    Comparative Study

    Fractional anisotropy and mean diffusivity measurements on normal human brain: comparison between low-and high-resolution diffusion tensor imaging sequences.

    • Nickolas Papanikolaou, Spyros Karampekios, Efrosyni Papadaki, Menelaos Malamas, Thomas Maris, and Nicholas Gourtsoyiannis.
    • Department of Radiology, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece. npapan@med.uoc.gr
    • Eur Radiol. 2006 Jan 1; 16 (1): 187-92.

    AbstractNon-invasive in vivo visualization of white matter fiber tracts is currently feasible by means of diffusion tensor imaging (DTI) techniques. DTI-derived metrics, like fractional anisotropy (FA) and mean diffusivity (MD), have the potential to improve tissue characterization. Technical optimization of diffusion tensor sequences, including signal-to-noise ratio and spatial resolution, was performed for 20 normal subjects. High- and low-resolution DTI sequences were applied on all subjects and FA, MD parametric maps were reconstructed for both protocols. Voxel-based statistical analysis revealed regions with significantly different FA and MD values between the two sequences, while the same type of analysis was performed to illustrate regions with significantly different signal-to-noise ratio. In conclusion, optimized DTI sequences may be applied routinely in clinical practice with a standard MR scanner, while accurate quantification of FA and MD may improve lesion characterization.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…