• Clinical nuclear medicine · Dec 2017

    Case Reports

    68Ga-Prostate-Specific Membrane Antigen-Avid Tubercular Lesions Mimicking Prostate Cancer Metastasis on Simultaneous Prostate-Specific Membrane Antigen PET/MRI.

    • Aashim Ahuja, Sangeeta Taneja, Kiran Thorat, and Amarnath Jena.
    • From the *Department of Molecular Imaging and Nuclear Medicine, Indraprastha Apollo Hospitals, Sarita Vihar, Delhi; and †Department of Laboratory Medicine, Sir H. N. Reliance Foundation Hospital, Prarthana Samaj, Girgaon, Mumbai, India.
    • Clin Nucl Med. 2017 Dec 1; 42 (12): e509-e510.

    AbstractGa-prostate-specific membrane antigen (PSMA) has gained increasing interest as a target molecule in imaging of prostate cancer because of its selective overexpression in local prostate cancer lesions and metastasis. We report a case of a 62-year-old man with raised serum prostate-specific antigen levels who presented for Ga-PSMA HBED-CC simultaneous PET/MRI for prostate cancer evaluation. A PSMA-nonavid PI-RADS 5 (Prostate Imaging-Reporting and Data System) lesion was confirmed as adenocarcinoma on histopathology. The PSMA-avid lesions were noted in the calvarium and lung, with the calvarial lesion confirmed to be of tubercular etiology on biopsy, and both lesions subsequently responded to antitubercular treatment.

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