• Clinical nuclear medicine · May 2011

    Atlas of confounding factors in head and neck PET/CT imaging.

    • Peeyush Bhargava, Saiyyeda Rahman, and Juliet Wendt.
    • Department of Nuclear Medicine and Radiology, Michael E. DeBakey VA Medical Center, Houston, TX, USA. Peeyush.bhargava@va.gov
    • Clin Nucl Med. 2011 May 1; 36 (5): e20-9.

    PurposeInterpretation of positron emission tomography/computed tomography (PET/CT) studies in the head and neck region is challenging due to the complex anatomy and nonspecific physiologic and inflammatory FDG uptake. We present an atlas of common confounding factors encountered at our institution.Materials And MethodsWe present whole-body fluorodeoxyglucose (FDG) PET/CT studies of 20 patients with various confounding factors in the head and neck. Most patients (15) had a history of head and neck cancer and some (5) of them presented with other primary tumors.ResultsWe describe these cases under the following categories: physiologic uptake (6), inflammatory uptake (5), unexpected benign tumors (2), unexpected malignant tumors (4), postradiation changes (2), postsurgical changes (2), and misregistration (1).ConclusionsKnowledge of common variants, pitfalls, and treatment effects is essential in accurate reading of PET/CT in the head and neck region.

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