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Radiol. Clin. North Am. · Sep 2009
ReviewHow to avoid nephrogenic systemic fibrosis: current guidelines in Europe and the United States.
- Henrik S Thomsen.
- Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3B, DK-Copenhagen N, Denmark. hentho01@heh.regionh.dk
- Radiol. Clin. North Am. 2009 Sep 1; 47 (5): 871-5, vii.
AbstractViews vary about how to avoid nephrogenic systemic fibrosis (NSF). In Europe, it is contraindicated to use gadodiamide, gadopentetate dimeglumine, and gadovertisamide in patients who have a glomerular filtration rate (GFR) of less than 30 mL/min, and these agents may only be used with caution in patients who have a GFR between 30 and 60 mL/min. Similar restrictions have not been introduced for the other six gadolinium-based contrast agents available in the European market. In the United States, the US Food and Drug Administration introduced a class ban and warned about the use of gadolinium-based contrast agents in patients who have reduced renal function. However, European and American guidelines about how to avoid NSF are generally not very different.
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