• Eur Addict Res · Jan 2005

    Case Reports

    Within-patient variability in clinical presentation of gamma-hydroxybutyrate withdrawal: a case report.

    • Anthony Glasper, Michael McDonough, and Jenny Bearn.
    • Drug Dependency Unit, St. George's Hospital, London, UK.
    • Eur Addict Res. 2005 Jan 1; 11 (3): 152-4.

    AbstractThe emergence of gamma-hydroxybutyrate (GHB) dependence in the UK is described, with specific reference to a case study of serial episodes of GHB withdrawal. Symptoms are broadly similar to those for alcohol withdrawal, and rapid deterioration into delirium is common in severe dependence. This case report reflects the variability in clinical presentation of GHB withdrawal and response to treatment, even within the same patient. It is concluded that GHB withdrawal requires vigorous clinical management, preferably on an elective basis, in an inpatient setting if dependence is severe.

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