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Ned Tijdschr Geneeskd · Oct 2001
Case Reports[Anaphylactic shock after injection of patent blue for sentinel lymph node biopsy].
- J C van der Horst, M J de Bock, and J H Klinkenbijl.
- Afd. Dermatologie, Ziekenhuis Rijnstate, Postbus 9555, 6800 TA Arnhem.
- Ned Tijdschr Geneeskd. 2001 Oct 27; 145 (43): 2086-8.
AbstractAfter being diagnosed with a melanoma, an 18-year-old woman developed anaphylactic shock following an intracutaneous injection of patent blue during a sentinel lymph node biopsy procedure. Intracutaneous allergy tests revealed positive reactions with patent blue (Bleu patenté V 'Guerbet') as well as with several anaesthetics and morphine. It was concluded that patent blue was the most probable causative agent for the anaphylactic reaction and that the possibility of such a reaction should be taken into consideration during sentinel node procedures. After a few days the operation was completed under epidural anaesthesia with technetium Tc 99m sulphur colloid being used to detect the sentinel node.
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