• Feilong Li, Xuqiang Liu, Fuqiang Wang, Zhiping Gu, Qianyuan Tao, Cong Yao, Xuwen Luo, and Tao Nie.
• Department of Orthopedics, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
• Bmc Musculoskel Dis. 2019 Nov 18; 20 (1): 550.

BackgroundThis meta-analysis aimed to compare the clinical outcomes and complications of minimally invasive plate osteosynthesis (MIPO) and open reduction-internal fixation (ORIF) in patients with proximal humeral fractures.MethodsWe searched PubMed, EMBASE, Ovid, and the Cochrane Library to identify all relevant studies from inception to April 2019. Cochrane Collaboration's Review Manage 5.3 was used for meta-analysis.ResultsSixteen studies involving 1050 patients (464 patients in the MIPO group and 586 patients in the ORIF group) were finally included. According to the meta-analysis, MIPO was superior to ORIF in operation time, blood loss, postoperative pain, fracture union time, and constant score. However, MIPO was associated with more exposure to radiation and axillary nerve injury. No significant differences were found in length of hospital stays and complication except for axillary nerve injury.ConclusionThe present evidence indicates that compared to ORIF, MIPO had advantages in functional outcomes, operation time, blood loss, postoperative pain, and fracture union time for the treatment of PHFs. However, the MIPO technique had a higher rate of axillary nerve injury and longer radiation time compared to ORIF.

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