• Medicina clinica · Jul 2021

    Case Reports Multicenter Study Observational Study

    Skin lesions in children during the first wave of the SARS-CoV-2 pandemic.

    • Begoña Carazo Gallego, Laura Martín Pedraz, Rocío Galindo Zavala, Mercedes Rivera Cuello, Concepción Mediavilla Gradolph, and Esmeralda Núñez Cuadros.
    • Unidad de Infectología Pediátrica, UGC Pediatría, Hospital Regional Universitario de Málaga, Málaga, España. Electronic address: bcarazo002@gmail.com.
    • Med Clin (Barc). 2021 Jul 9; 157 (1): 333733-37.

    BackgroundCutaneous manifestations have been included in COVID-19 patients' clinical spectrum. Our objective was to determine the association between skin lesions in children and SARS-CoV-2 infection, analyzing others possible infectious/autoimmune etiologies.Material And MethodsObservational, multicenter, cross-sectional study, about children with skin manifestations from April to May 2020. The diagnosis of SARS-CoV-2 was performed by PCR in nasopharyngeal exudate and/or presence of antibodies by serology.ResultsSixty-two children were included, 9 (14.5%) presented positive antibodies to SARS-CoV-2, with no positive PCR to SARS-Cov-2 in those patients in whom it was made. Patients with positive serology to SARS-CoV-2 presented chilblains and/or vesicular-bullous skin lesions more frequently (66.7% vs. 24.5%, p=0.019). Generalized, urticarial and maculopapular rash was more common in patients with negative antibodies (37.7 vs. 0%, p=0.047), others pathogens were isolated in 41.5% of these patients. There were no significant differences in the positivity for autoantibodies between both groups.ConclusionIn our study, the presence of chilblains-like and/or vesicular lesions were significantly related to SARS-CoV-2 previous contact.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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