• Daniel M Cornfeld, Gary Israel, Shirley M McCarthy, and Jeffery C Weinreb.
• Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA. daniel.cornfeld@yale.edu
• J Magn Reson Imaging. 2008 Jul 1; 28 (1): 121-7.

PurposeTo compare two T1-weighted (T1W) fat-suppressed sequences for 3D breath-hold pre- and postcontrast fat-suppressed T1W imaging of the female pelvis at 3T.Materials And MethodsPelvic MRI scans of 16 female patients were retrospectively identified who were scanned with two 3D breath-hold sequences: 1) a fast spoiled gradient echo sequence with spectral inversion at lipids (SPECIAL) (called 3D FSPGR), and 2) a dual-echo two-point Dixon (DE Dixon) sequence. Contrast between soft tissue and fat, soft tissue and fluid, and fat and fluid was measured on pre- and postcontrast images. Additionally, two readers subjectively scored the images for degree and homogeneity of fat suppression plus presence and severity of artifacts.ResultsContrast between muscle and myometrium to fat was improved with the Dixon technique (0.61 vs. 0.09 and 0.7 vs. 0.3, respectively, P < 0.001). Both readers agreed that fat suppression was stronger with the Dixon sequence (P < 0.001 and P = 0.06). Artifacts were equivalent (P = 0.53 and 0.65).ConclusionThe 3D DE Dixon sequence achieved stronger fat suppression in the female pelvis when compared to a 3D FSPGR sequence with SPECIAL.(c) 2008 Wiley-Liss, Inc.

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