• Pediatr Crit Care Me · Sep 2021

    Review

    Decision-Making, Ethics, and End-of-Life Care in Pediatric Extracorporeal Membrane Oxygenation: A Comprehensive Narrative Review.

    • Katie M Moynihan, Anna Dorste, Bryan D Siegel, Edon J Rabinowitz, Andrew McReynolds, and Tessie W October.
    • Department of Cardiology, Division of Cardiovascular Critical Care, Boston Children's Hospital Boston, MA.
    • Pediatr Crit Care Me. 2021 Sep 1; 22 (9): 806-812.

    ObjectivesPediatric extracorporeal membrane oxygenation is associated with significant morbidity and mortality. We sought to summarize literature on communication and decision-making, end-of-life care, and ethical issues to identify recommended approaches and highlight knowledge gaps.Data SourcesPubMed, Embase, Web of Science, and Cochrane Library.Study SelectionWe reviewed published articles (1972-2020) which examined three pediatric extracorporeal membrane oxygenation domains: 1) decision-making or communication between clinicians and patients/families, 2) ethical issues, or 3) end-of-life care.Data ExtractionTwo reviewers independently assessed eligibility using Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology.Data SynthesisOf 2,581 publications screened, we identified one systematic review and 35 descriptive studies. No practical guides exist for communication and decision-making in pediatric extracorporeal membrane oxygenation. Conversation principles and parent/clinician perspectives are described. Ethical issues related to consent, initiation, discontinuation, resource allocation, and research. No patient-level synthesis of ethical issues or end-of-life care in pediatric extracorporeal membrane oxygenation was identified.ConclusionsDespite numerous ethical issues reported surrounding pediatric extracorporeal membrane oxygenation, we found limited patient-level research and no practical guides for communicating with families or managing extracorporeal membrane oxygenation discontinuation.Copyright © 2021 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

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