• Catherine E Naber, Nonyerem O Acholonu, Neil D Fernandes, Brian P Sanders, Lauren Sweetser, Michael R Flaherty, Manuella Lahoud-Rahme, and Phoebe H Yager.
• Division of Pediatric Critical Care Medicine, Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, 175 Cambridge Street, 5(th) Floor, Boston, MA 02114, United States; Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, 175 Cambridge Street, 5(th) Floor, Boston, MA 02114, United States.
• Am J Emerg Med. 2021 Nov 1; 49: 300-301.

AbstractNaloxone is a medication with a largely benign safety profile that is frequently administered in the emergency department to patients presenting with altered mental status. Ventricular tachycardia has been reported after naloxone administration in adult patients with prior use of opiate or sympathomimetic medications. However, no such reports exist in the pediatric population or in patients who have no known history of opiate or sympathomimetic medication use. We describe a case of ventricular tachycardia after naloxone administration in a 17-year-old male with no known prior use of opiate or sympathomimetic agents who presented to the emergency department with altered mental status of unknown etiology. Emergency physicians may wish to prepare for prompt treatment of ventricular arrythmias when administering naloxone to pediatric patients presenting with altered mental status.Copyright © 2021 Elsevier Inc. All rights reserved.

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