• Rebekah Diamond, Avital Fischer, Benjamin Hooe, Taylor B Sewell, Adam Schweickert, Danielle Ahn, Nazreen Jamal, Philip Zachariah, Jennifer Cheng, Wanda Abreu, and Mirna Giordano.
• Department of Pediatrics, Columbia University Irving Medical Center, New York, New York; and rcd2143@cumc.columbia.edu.
• Hosp Pediatr. 2020 Sep 1; 10 (9): 810-819.

AbstractThe novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread quickly across the globe, creating unique and pressing challenges for today's physicians. Although this virus disproportionately affects adults, initial SARS-CoV-2 infection can present a significant disease burden for the pediatric population. A review of the literature yields descriptive studies in pediatric patients; however, no evidence-based or evidence-informed guidelines for the diagnosis and treatment of the hospitalized pediatric patient have been published in peer-reviewed journals. The authors, working at a quaternary care children's hospital in the national epicenter of the SARS-CoV-2 pandemic, found an urgent need to create a unified, multidisciplinary, evidence-informed set of guidelines for the diagnosis and management of coronavirus disease 2019 in children. In this article, the authors describe our institutional practices for the hospitalized pediatric patient with confirmed or suspected initial SARS-CoV-2 infection. The authors anticipate that developing evidence-informed and institution-specific guidelines will lead to improvements in care quality, efficiency, and consistency; minimization of staff risk of exposure to SARS-CoV-2; and increased provider comfort in caring for pediatric patients with SARS-CoV-2 infection.Copyright © 2020 by the American Academy of Pediatrics.

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