• Radiology · Nov 2008

    Comparative Study

    Peripheral MR angiography with blood pool contrast agent: prospective intraindividual comparative study of high-spatial-resolution steady-state MR angiography versus standard-resolution first-pass MR angiography and DSA.

    • Dariusch R Hadizadeh, Jürgen Gieseke, Stefan H Lohmaier, Kai Wilhelm, Jack Boschewitz, Frauke Verrel, Hans H Schild, and Winfried A Willinek.
    • Department of Radiology, University of Bonn, Bonn, Germany.
    • Radiology. 2008 Nov 1; 249 (2): 701-11.

    PurposeTo prospectively compare the accuracy of high-spatial-resolution steady-state magnetic resonance (MR) angiography with standard-resolution first-pass MR angiography in the lower extremities, with digital subtraction angiography (DSA) as the reference standard.Materials And MethodsInstitutional ethics committee approval and written informed consent were obtained. Twenty-seven patients (16 men, 11 women; mean age, 64.4 years +/- 14.8 [standard deviation]; range, 26-87 years) suspected of having or known to have peripheral arterial disease underwent first-pass and steady-state MR angiography and DSA. First-pass and steady-state MR angiography were performed in the same patient in the same session and with the same dose of blood pool contrast agent. The most severe stenosis grade of each evaluated segment was measured; sensitivity, specificity, and positive and negative predictive values were calculated at first-pass and steady-state MR angiography, with DSA as the reference standard. The kappa coefficient was used to measure the agreement between first-pass MR angiography, steady-state MR angiography, and DSA.ResultsA total of 334 arterial segments were available for intraindividual comparison of first-pass MR angiography, steady-state MR angiography, and DSA in 27 patients. In 20 (74%) of 27 patients, the stenosis grade of at least one of the evaluated vessels differed at steady-state MR angiography from that at first-pass MR angiography. In total, stenosis grade was judged as higher at first-pass MR angiography than at DSA (overestimation) in 28 of 334 segments and as lower (underestimation) in 15 of 334 segments. The stenosis grade as judged at steady-state MR angiography matched with that at DSA in 334 of 334 vessel segments.ConclusionHigh-spatial-resolution steady-state MR angiography allowed for better agreement with DSA regarding stenosis grade in patients with arterial disease compared with standard-resolution arterial-phase first-pass MR angiography.(c) RSNA, 2008.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…