• Medicina · Jan 2005

    Review

    [Autoimmunity in pathogenesis of chronic obstructive pulmonary disease].

    • Daiva Urboniene, Raimundas Sakalauskas, and Brigita Sitkauskiene.
    • Department of Pulmonology and Immunology, Institute for Biomedical Research, Kaunas University of Medicine, 50009 Kaunas, Lithuania. daivaurboniene@one.lt
    • Medicina (Kaunas). 2005 Jan 1; 41 (3): 190-5.

    AbstractFor years, smoking induced inflammatory reaction, comprised mainly of neutrophils and macrophages, has been accepted to be the major component in pathogenesis of chronic obstructive pulmonary disease. New developments in molecular and cell biology have provided scientists with new knowledge and understanding of inflammatory processes in lung. Recent reports have underlined the role of autoimmunity and T lymphocytes as a potential important factor, which takes place in the pathogenesis of chronic obstructive pulmonary disease. This article reviews potential mechanism of T cell mediated immune response in chronic obstructive pulmonary disease.

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