• Radiology · Nov 1992

    Comparative Study

    Intracranial lesion enhancement with gadolinium: T1-weighted spin-echo versus three-dimensional Fourier transform gradient-echo MR imaging.

    • S A Mirowitz.
    • Department of Radiology, Jewish Hospital at Washington University Medical Center, Washington University School of Medicine, St Louis, MO 63110.
    • Radiology. 1992 Nov 1; 185 (2): 529-34.

    AbstractThe conspicuity of lesion enhancement with gadopentetate dimeglumine was evaluated subjectively and quantitatively through calculation of contrast-to-noise ratios (C/Ns) on T1-weighted three-dimensional (3D) Fourier transform (FT) gradient-echo (GRE) and two-dimensional (2D) FT spin-echo (SE) images of the brain in 406 consecutive patients. One hundred one enhancing intracranial lesions were present in 61 patients, including intra-(n = 76) and extraaxial (n = 25) processes of neoplastic (n = 68), infectious or inflammatory (n = 13), ischemic (n = 11), or vascular (n = 9) origin. Enhancement was apparent in all lesions on 2DFT SE and 3DFT GRE images, with similar subjective conspicuity in 86.8% (87 of 101) of lesions. Quantitative C/N measurements for 2DFT SE (mean, 17.6) and 3DFT GRE (mean, 17.2) imaging were not significantly different (P = .72). These findings, along with the other advantages of 3DFT GRE imaging, indicate that 3DFT GRE examinations are likely to play a major role in the performance of contrast-enhanced MR imaging of the brain.

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