• J Asthma · Jan 2016

    Case Reports

    Early diagnosis based on clinical history and BALF for successful management of smoking-induced acute eosinophilic pneumonia without unnecessary antibiotic usage: a case report.

    • Jee In Song, Yang-Ki Kim, Jung Hwa Hwang, and Hyeon-Jong Yang.
    • a Department of Pediatrics .
    • J Asthma. 2016 Jan 1; 53 (4): 452-5.

    IntroductionAcute eosinophilic pneumonia (AEP) is a rapid onset and severe respiratory illness characterized by acute febrile respiratory insufficiency, eosinophilic infiltration in the lungs and unique findings on chest imaging. Difficulty in differentiating from other respiratory distress caused by community-acquired pneumonia may result in a delayed diagnosis or treatment with empirical antibiotics.Case StudySixteen-year-old boy who developed AEP with marked eosinophilia in bronchoalveolar lavage fluid (BALF, 36.6%), decreased diffusion capacity of the lung for carbon monoxide (62%) and unique radiological findings. Although he initially denied tobacco use, on repeated thorough clinical history questioning, he eventually admitted beginning smoking 19 days before the onset of symptoms with gradually increasing frequency.ResultsHis symptoms resolved quickly without use of antibiotics after cessation of tobacco and treatment with corticosteroids.ConclusionCareful clinical history taking regarding tobacco use combined with early examination of BALF and recognition of unique radiological findings are critical for proper management of AEP.

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