• Hengshan Ji, Jiang Wu, Guifen Yang, Chuanjin Sun, Hong Zhu, and Longjiang Zhang.
• Department of Nuclear Medicine, Jinling Hospital, Medical school of Nanjing University, Nanjing, Jiangsu Province,210002, China. zh_zy@163.com.
• Hell J Nucl Med. 2017 Jan 1; 20 (1): 97-99.

ObjectiveAdult liver Langerhans cell histiocytosis (LCH) is an extremely rare desease. This paper reports a 40 years old male patient who was diagnosed as liver LCH though ultrasound-guided liver biopsy. The initial Fluorrine-18- fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) showed multiple nodular low-density lesions in liver without obvious elevated 18F-FDG uptake. Four years later, the follow-up 18F-FDG PET/CT showed the liver multiple lesions with slightly elevated 18F-FDG uptake.ConclusionWe describe this case, to highlight the importance of 18F-FDG PET/CT in differential diagnosis for the primary disease and the multiple liver nodules.

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