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Clinical nuclear medicine · Apr 2004
Clinical TrialThe added value of spiral computed tomographic angiography after lung scintigraphy for the diagnosis of pulmonary embolism.
- L Radan, M Mor, S Gips, D Schlag-Eisenberg, Y Lurie, K Dickstein, H Bitterman, and S Ben-Haim.
- Department of Nuclear Medicine, Lady Davis Carmel Medical Center, Technion, Haifa, Israel.
- Clin Nucl Med. 2004 Apr 1; 29 (4): 255-61.
ObjectivesThe objectives of this study were to evaluate the added clinical value of spiral computed tomographic angiography (CTA) after ventilation-perfusion lung scintigraphy (V/Q) for the management of patients with suspected pulmonary embolism (PE).MethodsOf 987 patients who had V/Q during 2001, 64 patients (6%) had CTA performed for further evaluation. V/Q and CTA findings were retrospectively analyzed by 2 clinicians who were blinded to the patients' outcome. Patient management was determined based on clinical and V/Q data and was reassessed after the addition of CTA data.ResultsCTA was performed in 2 patients with normal V/Q, 16 patients with low probability, 28 patients with intermediate, 4 patients with high probability, and 14 patients with nonconclusive V/Q. Three patients (19%) with low probability, 9 (32%) with intermediate probability, 4 (29%) with nonconclusive, and 4 (100%) with high probability V/Q had PE diagnosed by CTA. CTA findings changed the management in 2 patients (13%) with low probability, 15 (54%) with intermediate probability, and 4 (29%) with nonconclusive V/Q.ConclusionIn our institution, V/Q remains the main imaging modality for evaluation of patients with clinically suspected PE. CTA was performed after V/Q in 6% of patients. Patients with intermediate probability and those with nonconclusive V/Q, and to a much lesser extent, patients with low probability V/Q could benefit from the addition of CTA after V/Q. In patients with normal V/Q and those with high-probability V/Q, the addition of CTA does not seem to influence patient management.
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