• Neuroradiology · Apr 2012

    Comparative Study

    Intracranial aneurysm coiling with PGLA-coated coils versus bare platinum coils: long-term anatomic follow-up.

    • Michel Piotin, Silvia Pistocchi, Bruno Bartolini, and Raphaël Blanc.
    • Department of Interventional Neuroradiology, Foundation Rothschild Hospital, Paris, France. mpiotin@free.fr
    • Neuroradiology. 2012 Apr 1; 54 (4): 345-8.

    IntroductionThe purpose of this study is to compare the long-term (≥12 months) angiographic follow-up of aneurysms treated with polymer polyglycolic-lactic acid (PGLA)-coated coils versus bare platinum coils.MethodsLong-term angiographic follow-up results of 90 aneurysms treated exclusively with PGLA-coated coils were retrospectively analyzed and compared to those of 158 aneurysms treated exclusively with bare platinum coils.ResultsThere were 32 ruptured aneurysms (35.5%) in the PGLA-coated coil group and 62 (39.2%) in the bare platinum coil group. The mean angiographic follow-up was 29 months in the PGLA-coated coil group versus 27 months in the bare platinum coil group (P = 0.2297). The mean time to angiographic recurrence was 14 months in the PGLA-coated coil group versus 18 months in the bare platinum coil group (P = 0.1088). Recurrence rates were 35.6% (32/90) and 31.0% (49/158) in the PGLA-coated coil and bare platinum coil groups, respectively (P = 0.4837). The major recurrence justifying retreatment was 5.6% (5/90) in the PGLA-coated coil group versus 6.7% (10/158) in the bare platinum coil group (P = 1.000).ConclusionPGLA-coated coils provided no better long-term recanalization rates than bare platinum coils.

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