• Radiology · Oct 2003

    In vivo proton MR three-dimensional T1rho mapping of human articular cartilage: initial experience.

    • Ravinder Reddy Regatte, Sarma V S Akella, Arijitt Borthakur, J Bruce Kneeland, and Ravinder Reddy.
    • MMRRCC, Department of Radiology, B1, Stellar-Chance Laboratories, University of Pennsylvania Medical Center, 422 Curie Blvd, Philadelphia, PA 19104-6100, USA. regatte@mail.mmrrcc.upenn.edu
    • Radiology. 2003 Oct 1; 229 (1): 269-74.

    AbstractThe purpose of this study was to demonstrate the feasibility of computing three-dimensional relaxation maps of spin-lattice relaxation time in the rotating frame (T1rho) from in vivo magnetic resonance (MR) images of the human patellofemoral joint. T1rho was measured by applying a three-dimensional gradient-echo pulse sequence in six healthy subjects and one symptomatic subject by using a 1.5-T MR imager and a 15-cm-diameter transmit-receive quadrature birdcage radiofrequency coil. Average T1rho measured in healthy patellar cartilage was 49.7 msec +/- 3.2 (mean +/- SD). Two-dimensional T1rho-weighted images were obtained with a fast spin-echo pulse sequence for comparison. There was good correlation between two-dimensional and three-dimensional T1rho values for the six healthy subjects (R2 = 0.88, slope = 1.16).Copyright RSNA, 2003

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