• Clin Geriatr Med · Feb 2015

    Review

    Obstructive sleep apnea and type 2 diabetes in older adults.

    • Karoline Moon, Naresh M Punjabi, and R Nisha Aurora.
    • Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA.
    • Clin Geriatr Med. 2015 Feb 1; 31 (1): 139-47, ix.

    AbstractBoth obstructive sleep apnea (OSA) and type 2 diabetes mellitus are commonly seen in older adults. Over the last decade, there has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes and related metabolic conditions such as insulin resistance and glucose intolerance. Intermittent hypoxemia and recurrent arousals in OSA trigger a repertoire of pathophysiological events, which can in turn alter glucose homeostasis and possibly increase the risk for type 2 diabetes. Conversely, there is evidence that type 2 diabetes may alter the progression and expression of sleep-disordered breathing. Copyright © 2015 Elsevier Inc. All rights reserved.

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