• Military medicine · May 2023

    Case Reports

    Chronic Exertional Compartment Syndrome Treated With Botulinum Toxin-A Yielding 36-Month Total Symptom Relief: A Case Report.

    • Maxwell Jensen, Robert Maxwell Lystrup, and Christopher E Jonas.
    • Tacoma, WA 98402, USA.
    • Mil Med. 2023 May 16; 188 (5-6): e1310e1313e1310-e1313.

    AbstractChronic exertional compartment syndrome (CECS) can be a debilitating condition observed in athletes, including military service members. Surgical fascial release, first described in 1956, has long been a standard treatment despite symptom recurrence in up to 45% of surgically treated military service members. A 2013 case series introduced intracompartmental Botulinum Toxin-A (BoNT-A) injections as a nonsurgical CECS treatment option, demonstrating efficacy for 15 of 16 patients. At the time of this submission, two additional case reports addressing BoNT-A injections for CECS have occurred. This case report describes a U.S. Military service member treated with ultrasound-guided BoNT-A for bilateral lower leg CECS. This patient achieved pain-free activities for 36 months with one treatment. This case, coupled with additional literature, supports consideration of BoNT-A as a potential long-term, nonsurgical alternative for CECS.© The Association of Military Surgeons of the United States 2021. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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