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- J Herlitz, D Elmfeldt, S Holmberg, I Málek, G Nyberg, K Pennert, L Rydén, K Swedberg, A Vedin, and F Waagstein.
- Am. J. Cardiol. 1984 Jun 25; 53 (13): 9D-14D.
AbstractDuring the 3-month blind treatment period there were 40 deaths in the metoprolol group compared with 62 deaths in the placebo group (p = 0.024). During the first year (after 3 months the 2 groups were treated similarly) there were 64 deaths in the metoprolol group vs 93 in the placebo group (p = 0.017) and during 2 years 92 patients died in the metoprolol group vs 120 in the placebo group (p = 0.043). The relative incidence of different causes of death did not differ significantly between the 2 treatment groups, indicating that metoprolol reduced all causes of death to the same extent as its effect on overall mortality.
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