• Ying-Huai Wang, Hong-Zheng Cheng, Kun Liu, Bin-Lin Cai, Yi Luo, Dan Kan, and Jie Zhang.
• Department of Otolaryngology, Wuhan Puren Hospital, Wuhan 430081, Hubei, China.
• Medicine (Baltimore). 2021 Jul 2; 100 (26): e26410e26410.

BackgroundDysphagia is a commonly occurring condition in nasopharyngeal carcinoma (NPC) patients after radiotherapy. There has been an increasing number of studies focused on assessing the use of acupuncture to manage dysphagia. Moreover, the quality of the research has gradually increased. The present research will be conducted to systematically evaluate the efficiency and safety of using acupuncture to treat cases of dysphagia after radiation therapy in NPC patients.MethodsLiterature search will include all potential randomized controlled trials using MEDLINE, Cochrane Library, Web of Science, EMBASE, Chinese National Knowledge Infrastructure, Chinese BioMedical Literature, and WanFang database from their inception to May, 2021 without language or publication status restrictions, to evaluate the efficiency and safety of using acupuncture to treat dysphagia cases following radiation therapy in NPC patients. A couple of independent authors will select related literature, extract data from studies, and estimate this risk in the bias of the selected study articles. In the instance of contrasting opinions, the outcome is mediated through discussion with a different independent author. The data synthesis and statistical analysis will be completed with the RevMan software (version 5.3).ResultsThis study will evaluate the efficiency and safety of using acupuncture to treat dysphagia cases after radiation therapy in NPC patients.ConclusionThis study will determine the suitability of acupuncture as an effective and safe intervention for dysphagia in NPC patients after radiotherapy.Ethics And DisseminationThe present study does not need ethical approval.Registration NumberMay 19, 2021.osf.io/f2cvt. (https://osf.io/f2cvt/).Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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