• Curr Opin Oncol · Nov 2008

    Review

    Erythropoietin in cancer-related anemia.

    • Martin H Fenner and Arnold Ganser.
    • Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany. fenner.martin@mh-hannover.de
    • Curr Opin Oncol. 2008 Nov 1; 20 (6): 685-9.

    Purpose Of ReviewErythropoiesis-stimulating agents reduce the transfusion requirements of anemic cancer patients receiving chemotherapy. Risks associated with the use of erythropoiesis-stimulating agents in cancer patients have more recently been identified.Recent FindingsSeveral recently published phase III trials and a meta-analysis have shown an increased risk of venous thromboembolism and a decreased survival in anemic cancer patients treated with erythropoiesis-stimulating agents.SummaryTo minimize risks associated with erythropoiesis-stimulating agent use in cancer patients, the most recent American Society of Clinical Oncology/American Society of Hematology clinical practice guidelines and Food and Drug Administration recommendations should be followed.

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