• Young-Chang P Arai, Atsuko Morimoto, Hiroki Sakurai, Yusuke Ohmichi, Shuichi Aono, Makoto Nishihara, Jun Sato, Takahiro Ushida, Shinsuke Inoue, Makoto Kurisuno, and Yuji Kobayashi.
• Multidisciplinary Pain Centre, Aichi Medical University, School of Medicine, 21 Karimata, Nagakutecho, Aichigun, Nagakute, Aichi, 480-1195, Japan. arainon@aichi-med-u.ac.jp
• J Anesth. 2013 Feb 1;27(1):62-5.

BackgroundCeliac plexus block (CPB) can be used for treating intra-abdominal visceral pain syndromes. The celiac plexus is the largest plexus of the sympathetic nervous system. Several nerve blocks have a marked effect on autonomic nervous activity. Furthermore, stellate ganglion block changes cardiac autonomic nervous activity. Thus, CPB could influence the sympathetic activity of the cardiac plexus. The aim of the present study was to see whether CPB modulated heart rate variability (HRV) in patients with pancreatic cancer.MethodsTwelve patients received neurolytic CPB using 14 ml absolute alcohol. Data recorded in a palm-sized electrocardiographic unit were analyzed for HRV.ResultsCPB using a neurolytic solution did not induce any significant changes in the low-frequency (LF)/high-frequency (HF) ratio of HRV (LF/HF, P = 0.4642). Furthermore, the procedure did not induce any significant changes in blood pressure (systolic, P = 0.5051; diastolic, P = 0.5180).ConclusionCPB did not induce any significant changes in HRV or hemodynamics.

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