• Medicina clinica · Feb 2022

    Influence of the degree of anaemia on the prognosis of older adults with heart failure (SPAN-HF study).

    • Jordi Grau Amorós, José Ángel García García, José Antonio Mira Escartí, Anna Serrado Iglesias, M Carmen Moreno García, Luis Manzano, M Angustias Quesada Simón, Melitón Francisco Dávila Ramos, Jesús Casado Cerrada, Álvaro González Franco, Manuel Montero-Pérez-Barquero, and en representación de los investigadores del Grupo RICA.
    • Hospital Municipal de Badalona, Badalona, España. Electronic address: 11426jga@comb.cat.
    • Med Clin (Barc). 2022 Feb 25; 158 (4): 167-172.

    ObjectiveTo assess whether a sustained optimal haemoglobin value in the 3 months after admission for heart failure (HF) decompensation reduces morbidity and mortality during the 12 months after admission for acute HF.Patients And MethodRetrospective study of the 1408 patients older than 65 years included in the RICA registry divided into 3 groups: no anaemia (group A), recovered anaemia (group B), and persistent anaemia (group C), according to haemoglobin levels on admission, and 3 months after discharge. Kaplan-Meier curves were constructed, comparing the groups using the log-rank test and a Cox regression model was performed to analyse survival.Results578 (41.1%), 299 (21.2%) and 531 (37.7%) were included in groups A, B and C, respectively. We recorded a total of 768 deaths and readmissions. There were 23 (4%), 12 (4%) and 49 (9.2%), (p=.001) individuals who died due to HF and 154 (27%), 73 (24%) and 193 (36%) (P<.001) admissions for this pathology, respectively. Patients with persistent anaemia had a higher risk of death (RR 1.29, 95% CI 1.04-1.61, P=.024) or readmission (1.92, 95% CI 1.16-3, 19; P=.012) due to HF.ConclusionsPersistent anaemia in the months after admission for HF increases morbidity and mortality in the subsequent year.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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