• Bo Yu, Mengmeng Sun, Zhihong Wang, Bing Zhu, Jingquan Xue, Wenjiang Yang, Xinyan Gao, Mujun Zhi, Jiazhen Cao, Jinying Zhao, Xuewei Zhao, Wu Liu, Fuchun Wang, and Tie Li.
• Chinese Medicine Science and Technology Exchange Center, Beijing, P. R. China.
• Am. J. Chin. Med. 2021 Jan 1; 49 (5): 1151-1164.

AbstractOne of the most important aspects of clinical acupuncture practice, like diabetic gastroparesis, is the selection of suitable acupoints. Furthermore, it is critical to examine the therapeutic impact differences between distal and local acupoints, as well as the prescription of their combination. In this study, diabetic gastroparesis rats were treated by needling Zhongwan (CV12) and Zusanli (ST36), and then used Single Photon Emission Computed Tomography-CT (SPECT-CT) technology to assess the effects of promoting gastric motility. In addition, morphological observation, immunohistochemical examination, and biomarker assays, such as determination of growth factor 1, motilin, and ghrelin contents in serum samples, were performed to better understand the impact of certain various acupuncture treatments. All of the therapies improved the symptoms of diabetic gastroparesis rats, according to the findings. Stimulating these acupoints, on the other hand, can have a different therapeutic effect. In addition, needling local and distal acupoints together can have an antagonistic or synergistic impact on specific physiological and biochemical indexes such as gastric motility, ghrelin, gastrin, and growth factor 1, among others. Our findings demonstrated the benefits of acupoints and acupuncture in the management of diabetic gastroparesis, as well as a new insight into acupuncture therapeutics.

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