• The Journal of pediatrics · Sep 2001

    Clinical Trial

    Serum ionized magnesium in post-traumatic headaches.

    • J C Marcus, B T Altura, and B M Altura.
    • Division of Pediatric Neurology, State University of New York-Health Sciences Center, Brooklyn, New York, USA.
    • J. Pediatr. 2001 Sep 1; 139 (3): 459-62.

    AbstractThe objective of this study was to determine the values of serum ionized magnesium, total magnesium, and ionized calcium/ionized magnesium ratios in children with headaches. One hundred thirty-five children with primary complaints of headaches were classified according to the criteria of the International Headache Society. Blood samples were obtained and tested for ionized magnesium (IMg(2+)), total magnesium, ionized calcium (ICa(2+)), and pH. The ICa(2+)/IMg(2+) ratio was calculated. Nine children were given a diagnosis of post-traumatic headache. Six of them had statistically significant (P <.05) lowered IMg(2+) levels and high ICa(2+)/IMg(2+) ratios. Abnormalities in serum IMg(2+) concentrations and ICa(2+)/IMg(2+) ratios were found in children with post-traumatic headaches, but total magnesium levels were normal.

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