• Aust N Z J Obstet Gynaecol · Feb 2021

    Randomized Controlled Trial

    Reaching under-screened/never-screened indigenous peoples with human papilloma virus self-testing: A community-based cluster randomised controlled trial.

    • Evelyn Jane MacDonald, Stacie Geller, Nokuthaba Sibanda, Kendall Stevenson, Lorna Denmead, Anna Adcock, Fiona Cram, Merilyn Hibma, Peter Sykes, and Bev Lawton.
    • Centre for Women's Health Research, Te Tātai Hauora O Hine, Faculty of Health, Victoria University of Wellington, Wellington, New Zealand.
    • Aust N Z J Obstet Gynaecol. 2021 Feb 1; 61 (1): 135-141.

    BackgroundIndigenous women in the high-income countries of Canada, Australia, New Zealand and USA, have a higher incidence and mortality from cervical cancer than non-Indigenous women. Increasing cervical screening coverage could ultimately decrease cervical cancer disparities.AimsTo increase cervical screening for under-screened/never-screened Māori women.Materials And MethodsThis study was a cluster randomised controlled trial. Inclusion criteria were women aged 25-69, last screened ≥4 years ago, in Northland, New Zealand. The intervention arm was the offer of a human papilloma virus (HPV) self-test and the control arm was the usual offer of standard care - a cervical smear. The primary outcome was rate of cervical screening in the intervention group compared to control in Māori, the Indigenous peoples of New Zealand. Six primary care clinics were randomly allocated to intervention or control.ResultsOf 500 eligible Māori women in the intervention arm, 295 (59.0%) were screened. Of 431 eligible Māori women in the control arm, 94 (21.8%) were screened. Adjusting for age, time since last screen, deprivation index, Māori women in the intervention arm were 2.8 times more likely to be screened than women in the control arm (95% CI: 2.4-3.1, P-value <0.0001).ConclusionsOffer of HPV self-testing could potentially halve the number of under-screened/never-screened Māori women and decrease cervical morbidity and mortality. These results may be generalisable to benefit Indigenous peoples facing similar barriers in other high-income countries.© 2020 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

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