• Oral Surg Oral Med Oral Pathol Oral Radiol · Aug 2012

    Comparative Study

    Comparison of various methods for quantification of apparent diffusion coefficient of head and neck lesions with HASTE diffusion-weighted MR imaging.

    • Junichiro Sakamoto, Yoshinori Sasaki, Mika Otonari-Yamamoto, and Tsukasa Sano.
    • Department of Oral and Maxillofacial Radiology, Tokyo Dental College, Chiba, Japan. sakamotojun@tdc.ac.jp
    • Oral Surg Oral Med Oral Pathol Oral Radiol. 2012 Aug 1; 114 (2): 266-76.

    ObjectivesThe purposes of this retrospective study were to compare various methods of apparent diffusion coefficient (ADC) measurement for head and neck lesions in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI) and determine the threshold ADC value for predicting malignancy.Study DesignHASTE DW images of 46 lesions (10 cysts, 14 benign tumors, and 22 malignant tumors) were studied retrospectively. The ADC values were compared among the 0-1000 method, 500-1000 method, and weighted linear regression (WLR) fit.ResultsThe highest overall accuracies of 83.3%, 86.1%, and 88.9% were obtained when ADC values of 1.24 × 10(-3) mm(2)/s (0-1000 method), 0.98 × 10(-3) mm(2)/s (500-1000 method), and 1.23 × 10(-3) mm(2)/s (WLR fit), respectively, were used for the threshold.ConclusionsThe present results indicate that ADC measurement with HASTE DWI is useful in predicting malignancy of head and neck lesions.Copyright © 2012 Mosby, Inc. All rights reserved.

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