• Thorsten Steinfeldt.
• Universitätsklinikum Gießen und Marburg, Standort Marburg. Thorsten.Steinfeldt@med.uni-marburg.de
• Anasthesiol Intensivmed Notfallmed Schmerzther. 2012 May 1;47(5):328-33; quiz 334.

AbstractPermanent nerve injury as a complication of peripheral regional anaesthesia is fortunately rare with an estimated incidence of 0,03%. However, transient neurological symptoms are more frequent with an occurrence of 3-8%. The pathophysiology and etiology of nerve injury depends on a number of different factors. The needle-nerve trauma, cytotoxicity of local anaesthetics, patient factors (i.e. morbidity) and factors which are related to surgical interventions should be considered. Regarding pathophysiology, trauma-related inflammation should be acknowledged as an important interference during nerve recovery. Needle-nerve contacts, nerve perforation and local cytotoxicity of local anaesthetics should be reduced to a minimum by application of nerve stimulation, ultrasound and an adequate dosage of local anaesthetics with less locotoxicity.© Georg Thieme Verlag Stuttgart · New York.

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