• J Pediatr Oncol Nurs · Mar 2017

    Review

    Challenges Evaluating Chemotherapy-Induced Peripheral Neuropathy in Childhood Cancer Survivors.

    • Caroline Mohrmann, Jane Armer, and Robert J Hayashi.
    • 1 Washington University School of Medicine, Saint Louis, MO, USA.
    • J Pediatr Oncol Nurs. 2017 Mar 1; 34 (2): 106-114.

    AbstractChildren treated for cancer are exposed to a variety of chemotherapeutic agents with known toxicity to the peripheral nervous system. The side effect of peripheral neuropathy can cause changes in sensation, function, and even cause pain. Although peripheral neuropathy is recognized by pediatric oncology nurses as an important and significant side effect, measuring neuropathy can be quite complex for clinical care and research efforts. With more children surviving a cancer diagnosis today, this issue is increasingly important for childhood cancer survivors. This article has reviewed existing literature examining peripheral neuropathy in childhood cancer survivors with particular interest paid to measurement tools available and needs for future research. It is important for nurses to choose appropriate measures for clinical care and research methods in order to have an impact on patients experiencing this condition.

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