• Nan Fang Yi Ke Da Xue Xue Bao · May 2007

    Randomized Controlled Trial

    [Phase IIa clinical trail of hemocoagulase acutus for injection].

    • Jun-jie Zhou, Zong-hai Huang, Jin-long Yu, Zhou Li, and Guang-jun Zhou.
    • Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. tiandansun@21cn.com
    • Nan Fang Yi Ke Da Xue Xue Bao. 2007 May 1; 27 (5): 644-6.

    ObjectiveTo evaluate the efficacy and safety of hemocoagulase acutus for injection and determine its curative dose.MethodsForty-five patients on abdominal surgeries were randomly allocated into 2 study groups and 1 control group. Thirty minutes before the operation, the patients in the study groups received intravenous hemocoagulase acutus at 1 U and 2 U, respectively, and control group had no treatment. The hemostatic time, hemorrhagic volume, and hemoagglutination were observed in all the groups.ResultsThe average hemorrhagic volume and hemorrhagic volume per square were significantly lower in the two study groups than in the control group (P<0.05), and the average hemorrhagic volume per square were significantly lower in study group 2 U than in the 1 U group (P<0.05). No significant differences were found in adverse effects between the 3 groups.ConclusionHemocoagulase acutus for injection has good hemostatic effect for controlling capillary hemorrhage at the abdominal incisions and can be safely used in the surgical patients.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…