-
- Hyungseok Jang, Fang Liu, Tyler Bradshaw, and Alan B McMillan.
- Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
- Magn Reson Med. 2018 Jun 1; 79 (6): 2912-2922.
PurposeIn this study, we propose a rapid acquisition for MR-based attenuation correction (MRAC) in positron emission tomography (PET)/MR imaging, in which an ultrashort echo time (UTE) image and an out-of-phase echo image are obtained within a single rapid scan (35 s) at high spatial resolution (1 mm3 ), which allows accurate estimation of a pseudo CT image using 4-class tissue classification (discrete bone, discrete air, continuous fat, and continuous water).MethodsIn dual-echo ramped hybrid encoding (dRHE), a UTE echo is directly followed by a second out-of-phase echo, in which hybrid spatial encoding combining single-point imaging and 3-dimensional radial frequency encoding is used to improve the quality of both images. Two-point Dixon reconstruction is used to estimate fat- and water-separated images, and UTE images are used to estimate bone. Air and bone segmentation is improved by using multiple UTE images with an advanced hybrid-encoding scheme that allows reconstruction of multiple UTE images. To evaluate the proposed method, dRHE-MRAC PET/MR brain imaging was performed in 10 subjects. Dice coefficients and PET reconstruction errors relative to CT-based attenuation correction were compared with existing system MRAC approaches.ResultsIn dRHE-MRAC, the Dice coefficients for soft tissue, air, and bone were respectively 0.95 ± 0.01, 0.62 ± 0.06, and 0.78 ± 0.05, which was a significantly improved result compared with existing approaches. In most brain regions, dRHE-MRAC showed significantly reduced PET error (less than 1%) with P values less than 0.05.ConclusionsDual-echo ramped hybrid encoding enables rapid and robust imaging for MRAC with a very rapid acquisition. Magn Reson Med 79:2912-2922, 2018. © 2017 International Society for Magnetic Resonance in Medicine.© 2017 International Society for Magnetic Resonance in Medicine.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*
,_underline_
or**bold**
. - Superscript can be denoted by
<sup>text</sup>
and subscript<sub>text</sub>
. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3.
, hyphens-
or asterisks*
. - Links can be included with:
[my link to pubmed](http://pubmed.com)
- Images can be included with:
![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
- For footnotes use
[^1](This is a footnote.)
inline. - Or use an inline reference
[^1]
to refer to a longer footnote elseweher in the document[^1]: This is a long footnote.
.