• Jun-Ma Yu, Hao Sun, Chao Wu, Chun-Shan Dong, Yao Lu, and Ye Zhang.
• *Department of Anesthesiology, The First People's Hospital of Hefei, Anhui Medical University †Department of Anesthesiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
• Surg Laparosc Endosc Percutan Tech. 2016 Dec 1; 26 (6): 449-454.

BackgroundLocal anesthetics infiltration is one consensus efficient strategy for pain relief after laparoscopic cholecystectomy (LC). The aim of this study was to investigate analgesia efficacy of incisional infiltration with ropivacaine plus dexmedetomidine.MethodsPatients scheduled for LC were assigned to 4 groups by different medications for trocar wound infiltration. The incidence of adverse events and the analgesic effect of ropivacaine combined with dexmedetomidine for incision infiltration were recorded.ResultsIncisional infiltration of ropivacaine combining with dexmedetomidine could significantly reduce postoperative pain and the amount of pethidine requirement. Furthermore, it could also reduce time to walk without assistance, improve the efficacy of analgesia and sleep quality during the first night after LC, but did not increase the incidence of surgical adverse events.ConclusionsThe use of ropivacaine and dexmedetomidine may be considered as an alternative treatment for postoperative pain in patients undergoing LC.

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