• Fen Feng, Yu-hong Li, Xin An, Feng-hua Wang, Rui-hua Xu, Zhi-zhong Pan, You-jian He, and De-sen Wan.
• Department of Medical Oncology, State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou, China.
• Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Sep 1; 12 (5): 471-3.

ObjectiveTo elucidate the efficacy and probable prognostic factors of surgical resection of pulmonary metastasis from colorectal cancer.MethodsClinical data and outcomes of 35 colorectal patients with pulmonary metastasis undergone pulmonary metastasectomy were analyzed retrospectively.ResultsMedian follow-up time was 48.0 months. The median overall survival time was 36.0 months. Five-year survival rate was 33.0%. Nineteen patients died of tumor progression. Sixteen patients were survival including survival with tumor (10 cases) and without tumor (6 cases). One patient was still alive without tumor for 164 months. Univariate analysis revealed that disease free interval (DFI) was a prognostic risk factor, while gender, age, primary tumor site, pulmonary metastasis size and location, surgical procedure, pre-surgical CEA level, re-metastasectomy did not show influence on the survival time after pulmonary metastasectomy.ConclusionsFor some selected patients with indication, pulmonary metastasectomy may be a potential curative method. DFI may be associated with the prognosis after pulmonary metastasectomy.

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