• Armin Huber, Carmel Hayes, Benedikt Spannagl, Johannes Rieber, Volker Klauss, Stefan Oswald Schoenberg, Maximilion Reiser, and Bernd Jürgen Wintersperger.
• Institut für Klinische Radiologie, Klinikum der LMU, Grosshadern, Marchioninistr. 15, 81377 München, Germany. Armin.Huber@ikra.med.uni-muenchen.de
• Acad Radiol. 2007 Dec 1; 14 (12): 1500-8.

Rationale And ObjectivesWe sought to show that phase-sensitive detection and a single-shot technique allow imaging of the heart for detection of myocardial infarction during a single breathhold without adaptation of the inversion time.Materials And MethodsThirty-five patients at 2 weeks to 3 months after Q-wave myocardial infarction were examined on a 1.5-T MR system 10 minutes after the administration of a double-dose extravascular contrast agent. In order to determine the optimal inversion recovery time (TI), a TI scout sequence was performed. An IR-turboFlash sequence with optimized TI was used as standard of reference. A phase-sensitive inversion recovery (PSIR) single-shot TrueFISP sequence, which allows imaging of nine slices during one breathhold (TR/TE/FA/BW: 2.2 ms/1.1 ms/60 degrees , 8 degrees /1220 Hz/Px) was used with a nominal TI of 200 ms. Spatial resolution was identical for both techniques: 1.3 mm x 1.8 mm x 8 mm. Infarct volumes, area of infarction on a selected slice, and scan time for imaging delayed contrast enhancement (DCE) were compared.ResultsThe mean values for the time of imaging DCE were 10 minutes 43 seconds for the IR turboFLASH and 17 seconds (P<.001) for the PSIR single-shot TrueFISP sequence. No significant difference was found for the mean values of the infarct volumes with 18.7 ml (IR turboFLASH) and 17.3 ml (PSIR single-shot TrueFISP). The values for the correlation coefficients of the infarct volumes and infarct areas of the two different techniques were r=0.95 (P<.004) and r=0.97 (P<.002). The regression equations were y=0.76+0.92*x and y=0.07+0.93*x, respectively.ConclusionsPSIR single-shot TrueFISP allows for accurate identification of myocardial infarction during a single breathhold with reduction of scan time by a factor of 38.

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