• Alberto Grassi, Cecilia Signorelli, Francisco Urrizola, Luca Macchiarola, Federico Raggi, Massimiliano Mosca, Kristian Samuelsson, and Stefano Zaffagnini.
• Laboratorio di Biomeccanica e Innovazione Tecnologica, IRCSS Istituto Ortopedico Rizzoli, Bologna, Italy; Clinica Ortopedica e Traumatologica II, IRCSS Istituto Ortopedico Rizzoli, Bologna, Italy; Dipartimento Scienze Biomediche e Neuromotorie-DIBINEM, Università di Bologna, Bologna, Italy.
• Arthroscopy. 2019 Apr 1; 35 (4): 1172-1182.

PurposeTo compare knee anatomical parameters of patients with failed anterior cruciate ligament reconstruction (ACL-R) with those of a control group of sex-matched patients with successful ACL-R.MethodsForty-three patients (34 male, 9 female) who experienced graft failure after ACL-R were enrolled in the failed group. These patients were matched to a control group of 43 patients who underwent primary ACL-R with a minimum follow-up of 24 months. On magnetic resonance imaging, the following parameters were evaluated: transepicondylar distance, lateral and medial femoral condyle widths, tibial plateau width, notch width index, and the ratio of width and height of the femoral notch, ratio between the height and depth of the lateral and medial femoral condyle, lateral and medial posterior tibial slopes, and anterior subluxation of the lateral and medial tibial plateau. Multivariate regression with backward elimination, including only the previously identified significant variables, defined the independent predictors for revision surgery.ResultsThe anatomical variables that were significantly different between the 2 study groups were lateral and medial posterior tibial slopes, anterior subluxation of the lateral and medial tibial plateau, medial tibial plateau width, lateral tibial plateau width, medial femoral condyle width, and transepicondylar distance; however, the multivariate regression analysis identified the lateral posterior tibial slope (LTPs), the anterior subluxation of the medial tibial plateau, and the medial femoral condyle width as significant independent predictors (P < .05). The LPTs had the highest coefficient and the highest sensitivity (88%) and specificity (84%) to identify failures when considering the optimal cutoff value of 7.4°.ConclusionsSeveral anatomical parameters have been identified that differ significantly between patients with failed ACL-R and those without a documented failure. The most accurate predictor of ACL failure was an LTPs >7.4°, with a sensitivity of 88% and specificity of 84%. Surgeons should consider measuring LTPs during preoperative assessment of ACL-injured patients, and patients with values >7.4° should be considered at high risk of ACL-R failure.Level Of EvidenceLevel III retrospective prognostic trial.Copyright © 2019 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

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