• J. Dermatol. · Dec 2013

    Case Reports

    Clinical analysis of leg ulcers and gangrene in rheumatoid arthritis.

    • Michiko Hasegawa, Yayoi Nagai, Yoko Sogabe, Tomoyasu Hattori, Chizuru Inoue, Etsuko Okada, Osamu Tago, and Osamu Ishikawa.
    • Department of Dermatology, Gunma University Graduate School of Medicine, Gunma, Japan.
    • J. Dermatol. 2013 Dec 1; 40 (12): 949-54.

    AbstractLeg ulcers are often complicated in patients with rheumatoid arthritis (RA), however, the etiology is multifactorial. We examined the cases of leg ulceration or gangrene in seven RA patients who were hospitalized over the past 3 years. One patient was diagnosed as having pyoderma gangrenosum. Although vasculitis was suspected in three patients, no histological evidence was obtained from the skin specimens. In these patients, angiography revealed the stenosis or occlusion of digital arteries. In the remaining three patients, leg ulcers were considered to be due to venous insufficiency. Treatment should be chosen depending on the causes of leg ulcers. © 2013 Japanese Dermatological Association.

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