• Andréia Nogueira Ramos, João Gabriel Rosa Ramos, and Juliana Dumet Fernandes.
• Universidade Federal da Bahia, Programa de Pós-graduação em Ciências da Saúde - Salvador (BA), Brasil.
• Rev Assoc Med Bras (1992). 2021 Jan 1; 67 (1): 77-82.

ObjectiveOculocutaneous albinism describes a group of pigmentary disorders that lead to skin sensitivity and predisposition to skin malignances.AimsTo analyze clinical and epidemiological data in oculocutaneous albinism patients and to determine the prevalence of malignant skin lesions, assessing possible risk factors for skin cancer.MethodsCross-sectional study evaluating epidemiological data, habits of sun exposure and sun protection, and clinical examination of albino patients followed in a reference dermatology outpatient clinic in Brasil. Our primary outcome was the occurrence of malignant skin lesions in biopsied tissues.ResultsOf 74 patients analyzed, 11 (15%) had one or more suspicious lesions and were biopsied, of which 8 (72.7%) patients presented with basal cell carcinomas, 7 (63.3%) presented with squamous cell carcinoma, and 1 (9%) presented with melanoma. Moreover, 32(43%) patients presented with actinic keratosis. Age, female gender, previous history of sunburn, history of malignant lesions and history of sun exposure without photoprotection were associated with the presence of malignant lesions.LimitationsUnicentric, non-aleatory sample.ConclusionsThere was a high prevalence of malignant and pre-malignant lesions in this population. Some potentially modifiable risk factors were associated with the occurrence of malignant skin lesions.

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