• Diego Castillo, Albert Sánchez-Font, Virginia Pajares, Tomás Franquet, Roger Llatjós, Irene Sansano, Jacobo Sellarés, Carmen Centeno, Juan J Fibla, Marcelo Sánchez, José Ramírez, Amalia Moreno, Juan Carlos Trujillo-Reyes, Enric Barbeta, María Molina-Molina, Alfons Torrego, and por el grupo de trabajo CRIOMPID.
• Servicio de Neumología, Hospital de la Santa Creu i Sant Pau, Barcelona, España. Electronic address: dcastillo@santpau.cat.
• Arch. Bronconeumol. 2020 Feb 1; 56 (2): 99-105.

AbstractThe diagnosis of idiopathic pulmonary fibrosis (IPF) is a complex process that requires the multidisciplinary integration of clinical, radiological, and histological variables. Due to its diagnostic yield, surgical lung biopsy has been the recommended procedure for obtaining samples of lung parenchyma, when required. However, given the morbidity and mortality of this technique, alternative techniques which carry a lower risk have been explored. The most important of these is transbronchial cryobiopsy -transbronchial biopsy with a cryoprobe- which is useful for obtaining lung tissue with less comorbidity. Yield may be lower than surgical biopsy, but it is higher than with transbronchial biopsy with standard forceps. This option has been discussed in the recent clinical guidelines for the diagnosis of IPF, but the authors do not go so far as recommend it. The aim of this article, the result of a multidisciplinary discussion forum, is to review current evidence and make proposals for the use of transbronchial cryobiopsy in the diagnosis of IPF.Copyright © 2020. Publicado por Elsevier España, S.L.U.

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