• Der Nervenarzt · Apr 2004

    Case Reports

    [Long-term treatment of phantom- and stump pain with Botulinum toxin type A over 12 months. A first clinical observation].

    • U Kern, C Martin, S Scheicher, and H Müller.
    • Schmerztherapie/Fachbereich für Neurologie, Deutsche Klinik für Diagnostik, Wiesbaden. kern.neuro@dkd-wiesbaden.de
    • Nervenarzt. 2004 Apr 1; 75 (4): 336-40.

    AbstractRecently we were able to describe the successful treatment of phantom pain and stump pain with botulinum toxin A in a first pilot study. This case report over a 1-year period now demonstrates that long-term treatment for this indication is possible. We injected 4 x 25 IU of botulinum toxin A (Botox) into trigger points of the stump muscles of a lower limb amputee who suffered from severe phantom and stump pain. With four injections performed every 3 months, the patient became almost completely pain-free, and his intrathecal morphine therapy could be reduced to 40% of the initial dose. Intrathecal clonidine was eliminated completely, as were the oral analgesics. A surgical treatment suggested for the stump pain was no longer necessary, and we suppose that botulinum toxin can also improve the tolerance of artificial limbs in cases of stump pain.

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