• Shantanu Sinha and Usha Sinha.
• Muscle Imaging and Modeling Laboratory, Department of Radiology, University of California, San Diego, California 92121-0852, USA. shsinha@ucsd.edu
• J Magn Reson Imaging. 2011 Jul 1; 34 (1): 107-19.

PurposeTo investigate the reproducibility of diffusion tensor imaging (DTI) -derived indices and fiber architecture of calf muscles at 1.5 Tesla (T), to establish an imaging based method to confirm ankle position, and to compare fiber architecture at different ankle positions.Materials And MethodsSix subjects were imaged at 1.5T with the foot in neutral and plantarflexed positions. DTI indices were calculated in four muscle compartments (medial and lateral gastrocnemius [MG, LG], superficial and deep anterior tibialis [AT-S, AT-D]). Two subjects were scanned on 3 days to calculate the coefficient of variability (CV) and the repeatability coefficient (RC).ResultsDTI indices were close to the values obtained in earlier 3T and 1.5T studies. Fractional anisotropy decreased significantly in the MG and increased significantly in the AT-S and AT-D compartments while fiber orientation with respect to the magnet Z-axis increased significantly in the MG and decreased significantly in the AT-S compartment with plantarflexion. The CV and RC for the DTI indices and fiber orientations were comparable to 3T studies. Fiber lengths and orientation angles in the MG matched corresponding measures from ultrasound studies.ConclusionDTI at 1.5T provides reproducible measures of diffusion indices and fiber architecture of calf muscle at different muscle lengths.Copyright © 2011 Wiley-Liss, Inc.

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