• J Magn Reson Imaging · Sep 2008

    Parallel imaging enhanced MR colonography using a phantom model.

    • Martina M Morrin, Ivan Pedrosa, Charles A McKenzie, Richard J Farrell, Nicolas Bloch, Stephanie Solazzo, Long Ngo, Shraga N Goldberg, and Neil M Rofsky.
    • Department of Radiology, Beaumont Hospital, Dublin, Ireland. mmorrin@rcsi.ie
    • J Magn Reson Imaging. 2008 Sep 1; 28 (3): 664-72.

    PurposeTo compare various Array Spatial and Sensitivity Encoding Technique (ASSET)-enhanced T2W SSFSE (single shot fast spin echo) and T1-weighted (T1W) 3D SPGR (spoiled gradient recalled echo) sequences for polyp detection and image quality at MR colonography (MRC) in a phantom model. Limitations of MRC using standard 3D SPGR T1W imaging include the long breath-hold required to cover the entire colon within one acquisition and the relatively low spatial resolution due to the long acquisition time. Parallel imaging using ASSET-enhanced T2W SSFSE and 3D T1W SPGR imaging results in much shorter imaging times, which allows for increased spatial resolution.Materials And MethodsUsing two porcine colon phantoms each with eight simulated 3-10-mm "polyps," baseline reference sequences acquired without ASSET (6-mm slices and readout bandwidth [BW] 62 kHz) were compared with 11 SSFSE and 8 SPGR sequences acquired with 2-fold ASSET acceleration. ASSET-enhanced SSFSE and SPGR sequences comprised BW/matrix combinations ranging from 20-62 kHz/256-352x256, respectively, with slice thicknesses adjusted from 3.0 to 4.5 mm to maintain a 23-26-second acquisition time and 30 cm slab thickness. Two experienced radiologists viewed the datasets in a randomized, blinded fashion.ResultsCompared to reference sequences, ASSET-enhanced SSFSE and SPGR sequences facilitated better polyp detection and had similar overall image quality and per-phantom specificity. The two best ASSET-enhanced SSFSE (3 and 4.5 mm slices, each with BW of 62.5 kHz and 352x256 matrices) and three best ASSET-enhanced SPGR BW/slice thickness/matrix combinations of 31 kHz/4.4 msec/192x256; 62/3.4/192x256; and 62/4.0/192x256, respectively, permitted detection of all polyps>or=5 mm.ConclusionParallel imaging using ASSET-enhanced T2W SSFSE and T1W 3D SPGR improves the ability to detect significant colon polyps in an MRC phantom model.Copyright (c) 2008 Wiley-Liss, Inc.

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