• Anesthesia and analgesia · Dec 2009

    Randomized Controlled Trial

    Systemic lidocaine decreased the perioperative opioid analgesic requirements but failed to reduce discharge time after ambulatory surgery.

    • Allannah McKay, Antje Gottschalk, Annette Ploppa, Marcel E Durieux, and Danja S Groves.
    • Department of Anesthesia, University of Virginia, Charlottesville, VA 22908-0710, USA.
    • Anesth. Analg. 2009 Dec 1;109(6):1805-8.

    BackgroundIn this randomized, blinded, placebo-controlled trial, we evaluated whether systemic lidocaine would reduce pain and time to discharge in ambulatory surgery patients.MethodsSixty-seven patients were enrolled to receive lidocaine or saline infusion perioperatively.ResultsLength of postanesthesia care unit (PACU) stay did not differ between groups. Intraoperative opioid use was significantly less in the lidocaine group, both in the PACU and during the total study period but not after discharge. In the PACU, patients in the lidocaine group reported less pain (visual analog scale score 3.1 +/- 2.04 vs 4.5 +/- 2.9; P = 0.043). There were no differences in postoperative nausea and vomiting.ConclusionPerioperative systemic lidocaine significantly reduces opioid requirements in the ambulatory setting without affecting time to discharge.

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    This article appears in the collections: Lignocaine and Does intravenous lidocaine/lignocaine improve post-operative recovery?.

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