• Mini Rev Med Chem · Jun 2008

    Review

    Pharmacological strategies for neuroprotection in traumatic brain injury.

    • J S Jennings, A M Gerber, and M L Vallano.
    • Department of Neurosurgery, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
    • Mini Rev Med Chem. 2008 Jun 1; 8 (7): 689-701.

    AbstractTraumatic brain injury affects over a million Americans annually, but pharmacological therapy remains limited. Current standards of care in acute, subacute and chronic phases of injury are primarily supportive. This review discusses pharmacological strategies and future directions in patient treatment emphasizing pleiotropic agents targeting inflammation, oxidative damage, and glutamate excitotoxicity.

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