• Ueli Studler, Lawrence M White, Gustav Andreisek, Sheena Luu, Hai-Ling Margaret Cheng, and Marshall S Sussman.
• Department of Medical Imaging, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada. studleru@uhbs.ch
• J Magn Reson Imaging. 2010 Aug 1; 32 (2): 394-8.

PurposeTo evaluate the impact of motion on T1 values acquired by using either inversion-recovery fast spin echo (IR-FSE) or three-dimensional (3D) spoiled gradient recalled-echo (SPGR) sequences for delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) in volunteers.Materials And MethodsSingle-slice IR-FSE and 3D SPGR sequences were applied to perform dGEMRIC in five healthy volunteers. A mutual information-based approach was used to correct for image misregistration. Displacements were expressed as averaged Euclidean distances and angles. Averages of differences in goodness of fit (Deltachi(2)) tests and averages of relative differences in T1 values (DeltaT1) before and after motion correction were computed.ResultsMaximum Euclidean distance was 3.5 mm and 1.2 mm for IR-FSE and SPGR respectively. Mean +/- SD of Deltachi(2) were 10.18 +/- 8.4 for IR-FSE and -1.37 +/- 5.5 for SPGR. Mean +/- SD of DeltaT1 were 0.008 +/- 0.0048 for IR-FSE and -0.002 +/- 0.019 for FSPGR. Pairwise comparison of Deltachi(2) values showed a significant difference for IR-FSE, but not for 3D-SPGR. Significantly greater variability in T1 values was also noted for IR-FSE than for 3D-SPGR.ConclusionInvoluntary motion has a significant influence on T1 values acquired with IR-FSE, but not with 3D-SPGR in healthy volunteers.2010 Wiley-Liss, Inc.

21 keywords...

hide…