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- Y Ishii, H Tanizawa, and Y Takino.
- School of Pharmaceutical Sciences, University of Shizuoka, Japan.
- Biol. Pharm. Bull. 1993 Oct 1; 16 (10): 1040.
AbstractAs individual differences in sensitivity in the laxative activity of barbaloin were observed in rats, a selection test for barbaloin (31.1 mg/kg, p.o.) was carried out between 1989 and 1991. The annual percentages of rats exhibiting a reaction positive to barbaloin were almost constant (about 57%). We propose that rats positive to barbaloin should be selected for studies on the laxative effect of barbaloin.
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